8h30 - Welcome
Chairemen: Dr G. Rodier
8h50 - Conference Opening
Dr Felix Rey, Department of Virology, Institut Pasteur, Paris, France
9h00 - General Introduction
Recall of the facts: origin of the avian epidemic, first concerned countries…
Latest data about the epidemic: how much countries concerned, how much human cases…
Conclusions of the November 2005 WHO meeting in Geneva, Switzerland
Dr Guenael Rodier, WHO Europe, Communicable Disease Surveillance and Response, Copenhague, Denmark
9h30 - Economic Impact of the Avian Influenza Propagation
Impact on the poultry industry and the global economy of South East Asia
Impact on public health worldwide
Mr Milan Brahmbhatt, Lead Adviser in the East Asia Region of the World Bank Group, Washington DC, USA
10h00 - The need of a global task force for influenza
Pr Albert Osterhaus, National Influenza Centre and Department of Virology, Erasmus Medical Centre Rotterdam, Rotterdam, The Netherlands
10h30 - Break and Poster Session
Chairemen: Dr M. De Jong, Dr D. Swayne
11h00 - The Widening Host Range and Changing Pathobiology of Eurasian H5N1 Avian Influenza in Domestic and Wild Birds
What are the clinical signs and lesions of the avian flu in poultry?
What is the kind of birds affected?
Ecology and changes in the H5N1 HPAI as expressed in broader avian host range
What adaptation of the virus to new bird species?
Dr David Swayne, Southeast Poultry Research Lab, Agricultural Research Service, Athens, Georgia, USA
11h30 - Influenza H5N1 : diagnosis and disease
What kind of diseases and consequences for human health?
What are the tools for early detection of the virus?
Dr Menno D. de Jong, Department of Virology, Oxford University Clinical Research Unit (OUCRU), Hospital for Tropical Diseases, Ho Chi Minh City, Viet Nam
12h00 - Risks of H5N1 mutations and mammalian adaptation
Dr Erich Hoffman, Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, USA
12h30 - Short Oral Communication
12h40 - Lunch and Poster Session
14h00 - Role of Mathematical Modelling in Pandemic Preparedness
What tools are used to make this kind of study?
What are the results of the latest modelling?
Based on these simulations, which kind of actions have to be applied to avoid a human pandemic?
Dr Simon Cauchemez, Department of Infectious Diseases Epidemiology, Imperial College London, United Kingdom
14h30 - Short Oral Communications
Charmen: Pr E. De Clercq, Dr L. Chernomordik, Dr E. Hoffmann
14h50 - Avian influenza in humans: existing treatments, their limits, and new perspectives
Tamiflu, Relenza, Amantadine, Rimantadine and others
Pr Erik De Clercq, Virology and Chemotherapy Section, Department of Microbiology and Immunology, Rega Institute for Medical Research, Katholieke Universiteit Leuven, Leuven, Belgium
15h20 - Short Oral Communication
15h30 - Break and Poster Session
16h00 - Multivalent lectins as inhibitors of viral fusion and entry in cells: new antiviral mechanism
Dr Leonid Chernomordick, Section on Membrane Biology, Laboratory of Cellular and Molecular Biophysics, National Institute of Child Health and Human Development, Bethesda, Maryland,USA
16h30 - In silico docking on grid infrastructures to accelerate structure-based design against Influenza A Neuraminidases
Finding potential compounds that can inhibit the activities of Influenza A neuraminidase N1 subtype variants.
Accelerating the discovery of novel potent inhibitors through minimizing non-productive trial-and-error approaches.
Improving the efficiency of high throughput screening thanks to the grid infrastructure.
Dr Nicolas Jacq or Dr Vincent Breton, Laboratoire de Physique Corpusculaire of Clermont-Ferrand, CNRS/IN2P3, University of Clermont Ferrand, Aubière, France
17h00 - Electrochemical Influenza Surveillance System
Dr Dominic Suciu, CombiMatrix Corporation, Mukilteo,USA
17h15 - The use of real-time NASBA for the diagnosis of H5N1 Influenza and other respiratory viruses
Dr Guy Vernet, Director of the Emerging Pathogens R&D Department, Biomérieux, Marcy L’Etoile, France
17h30 - Short Oral Presentation
17h50 - Detection of avian influenza A/H5 viral isolates with highly sensitive, specific and inclusive real-time RT-PCR assays
Dr Olga Petrauskene, Applied Biosystems, Foster City, USA
18h05 - Discussion : What are the perspectives of Influenza treatment?
In the presence of the Scientific Committee
19h30 - Gala Dinner
On the Seine, on board of the cruising restaurant boat "Le Capitaine Fracasse"
Chairemen: Pr S. Van der Werf, Dr S. Sambhara
9h00 - The international response on avian influenza
The terrestrial animal health code
International standards
Vaccination
Short/medium and long term actions on global, regional and national level
Dr Christianne Bruschke, OIE, Paris, France
9h30 - Strategies to prevent avian influenza in humans in a non pandemic frame
How to avoid the transmission of the virus from animal to human?
Isolation in health care facilities
Health care worker exposures
Precautions for household and close contacts
Precautions for travelers
Pr Didier Houssin, Interministry Delegate for the Fight against Avian Influenza, French Ministry of Health, Paris, France
10h00 - Prevention through immunization: latest advances on vaccination
New adjuvants
Reverse genetics
Pr Sylvie Van der Werf, Génétique Moléculaire des Virus Respiratoires - URA 1966 CNRS, Pasteur Institute, Paris, France
10h30 - Break and Poster Session
11h00 - Development of adenoviral-vector-based pandemic influenza vaccine against antigenically distinct human H5N1 strains in mice
Dr Suryaprakash Sambhara, Centers for Disease Control and Prevention, Atlanta, USA
11h30 - Short Oral Communications
11h50 - Antiviral effect of catechins in green tea on influenza virus
Pr Baik-Lin Seong, Department of Biotechnology, College of Engineering, Yonsei University, Seoul 120-749, South Korea
12h20 Pandemic Influenza: a potential role for statins in treatment and prophylaxis
Pr David Fedson, Former Professor of Medicine, University of Virginia School of Medicine, Sergy Haut, France
12h35 - Short Oral Communication
12h40 - Lunch and Poster Session
Chairemen: Pr K Van der Velden, Pr Jean Philippe Derenne
14h00 - How to manage a Human Pandemic of Avian Influenza? Is Europe ready?
What are the different phases of a pandemic?
What are the measures set up by the governments?
What are the recommendations for individuals and public organisms in case of a pandemic?
Pr Jean Philippe Derenne, Department of Pneumology, La Pitié Salpêtrière Hospital, Paris, France
14h30 -Ethical Challenges in Pandemic Planning
How to minimize the differences in means between rich and poor countries in the fight against a pandemic?
How and to whom should the doses of vaccines be distributed in priority: to infected patients or in prevention to people important for the maintenance of the economical?
How to avoid or minimize the impact of travel restrictions and quarantine?
Dr Ross E.G. Upshur, Joint Centre for Bioethics Flu Pandemic Working Group Member, University of Toronto, Toronto, Canada
15h00 - Round Table Discussion in presence of emergency medical doctors, general medical doctors, crisis management specialists and the scientific committee: is the medical profession ready to fight against a pandemic? Is the world ready to face a human avian flu pandemic?
Is the medical profession well informed and trained?
What are the recommendations for the health workers?
What are the solutions to face the vaccine shortage? (example: to improve the vaccine efficiency)
How to avoid a funnel effect in the emergency room?
What would be the ideal organization in the hospital to manage a pandemic?
Round Table Chairman: Pr Koos Van der Velden (Chairman of the European Influenza Surveillance Scheme)
In the presence of Dr Anne Mosnier, National Coordinator of the French Group of Regional Influenza Observation (GROG) and Monsieur le Député Jean Marie Le Guen, President of the parlementary mission on Avian Influenza, Member of the French Assemblée Nationale
15h45 - Conclusion and Recommendations by the scientific committee